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Blood Reviews
Volume 24, Issue 4
, Pages 151-162
, July 2010
Anticoagulation in neonates and children: Pitfalls and dilemmas
References
- . Acquired antithrombin III deficiency secondary to asparaginase therapy in childhood acute lymphoblastic leukaemia. Blood Coagul Fibrinolysis. 1994;5(Suppl 1):S24–S36discussion S59–64
- . Neonatal thrombosis: Report of a prospective Canadian and international registry. Pediatrics. 1995;96(5 Pt 1):939–943
- Factor V Leiden, protein C, and lipoprotein (a) in catheter-related thrombosis in childhood: A prospective study. J Pediatr. 1997;131(4):608–612
- Anticoagulation and pediatric extracorporeal membrane oxygenation: Impact of activated clotting time and heparin dose on survival. Ann Thorac Surg. 2007;83(3):912–919discussion 919-20
- . Thrombembolism in childhood: A prospective 2
year BPSU study in the United Kingdom. Thromb Haemost. 2003;1(Suppl1):OC422 - Anticoagulation therapy in pediatric patients with sinovenous thrombosis: A cohort study. Arch Neurol. 1998;55(12):1533–1537
- . Arterial thromboembolic complications in pediatric patients. In: Thromboembolic complications during infancy and childhood. Hamilton, B.C: Decker Inc; 2000;p. 165–200
- Heparinase-modified thrombelastography in term and preterm neonates. Anesth Analg. 2004;98(6):1650–1652
- . Low-molecular-weight heparin-induced thrombocytopenia in a child. Ann Pharmacother. 2004;38(2):247–250
- . Acute idiopathic portal vein thrombosis in a child: A case report and literature review. Thromb Res. 2006;117(3):279–281
- . Thrombotic events revisited in children with acute lymphoblastic leukemia: Impact of concomitant Escherichia coli asparaginase/prednisone administration. Thromb Res. 2001;103(3):165–172
- A cross-sectional study evaluating post-thrombotic syndrome in children. Thromb Res. 2003;111(4–5):227–233
- Brachial artery thrombosis in infants: An algorithm for limb salvage. Plast Reconstr Surg. 2006;117(5):1481–1488
- . Age-related plasma reference ranges for two heparin binding proteins — vitronectin and platelet factor 4. Int J Lab Hematol. 2009;31(6):683–687
- . Anticoagulation clinics for children achieve improved warfarin management. Thromb Res. 2004;114(1):5–9
- . A survey of pediatric cardiology nurses' understanding of warfarin therapy. Pediatr Cardiol. 2006;27(2):204–208
- Enhanced thrombin regulation during warfarin therapy in children compared to adults. Thromb Haemost. 1998;80(4):570–574
- . Antithrombotic therapy in children. Chest. 2001;119(1 Suppl):344S–370S
- Analysis of warfarin therapy in pediatric patients: A prospective cohort study of 319 patients. Blood. 1999;94(9):3007–3014
- An open-label randomized controlled trial of low molecular weight heparin compared to heparin and coumadin for the treatment of venous thromboembolic events in children: The REVIVE trial. Thromb Res. 2003;109(2–3):85–92
- . Incidence of major bleeding in a large paediatric cohort of patients requiring warfarin therapy. J Thromb Haemost. 2005;3(Suppl 1):OR357
- . Erfahrungen mit der antikoagulatientherapie bei 10 patienten an der Univ Kinderklinik Erlangen, in Thrombosen im Kindersalter. In: Sutor AH editors. Basel: Editiones Roche; 1992;
- . Tracheobronchial calcification: An observation in three children after mitral valve replacement and warfarin sodium therapy. Radiology. 1990;176(3):728–730
- Reduced bone density in children on long-term warfarin. Pediatr Res. 2005;57(4):578–581
- . Osteoporosis: A potential complication of long term warfarin therapy. Thromb Haemost. 1999;Supply:1333a
- Capillary whole blood monitoring of oral anticoagulants in children in outpatient clinics and the home setting. Pediatr Cardiol. 2000;21(4):347–352
- . Home monitoring of warfarin therapy in children with a whole blood prothrombin time monitor. J Pediatr. 1995;127(3):389–394
- . Point-of-care antithrombotic monitoring in children. Thromb Res. 2006;118(1):113–121
- . Whole blood international normalization ratio measurements in children using near-patient monitors. J Pediatr Hematol Oncol. 2003;25(1):33–37
- Point-of-care monitoring of oral anticoagulation therapy in children. Comparison of the CoaguChek XS system with venous INR and venous INR using an International Reference Thromboplastin preparation (rTF/95). Thromb Haemost. 2009;102(1):159–165
- . Oral anticoagulant drugs. N Engl J Med. 1991;324(26):1865–1875
- Developmental haemostasis impact for clinical haemostasis laboratories. Thromb Haemost. 2006;95(2):362–372
- Monitoring unfractionated heparin (UFH) therapy: Which anti factor Xa assay is appropriate?. Thromb Res. 2006;120(3):347–351
- . Therapeutic range for unfractionated heparin therapy: Age-related differences in response in children. J Thromb Haemost. 2006;4(10):2280–2282
- . Age-specific differences in binding of heparin to plasma proteins. J Thromb Haemost. 2010;8(6):1290–1294
- Age is a determinant factor for measures of concentration and effect in children requiring unfractionated heparin. Thromb Haemost. 2010;103(5):
- Unfractionated heparin pharmacokinetic profile in children, in XXII Congress, International Society on Thrombosis and Haemostasis. 2009;Boston
- Heparin therapy in pediatric patients: A prospective cohort study. Pediatr Res. 1994;35(1):78–83
- . A clinically significant incidence of bleeding in critically ill children receiving therapeutic doses of unfractionated heparin: A prospective cohort study. Haematologica. 2007;92(2):244–247
- . Heparin-induced osteopenia: An appraisal. Adv Exp Med Biol. 1975;52:375–387
- . Heparin therapy and bone fractures. Lancet. 1992;340(8827):1098
- . Pathology of osteopathy following heparin therapy. Dtsch Med Wochenschr. 1969;94(45):2334–2338
- . Heparin-induced osteoporosis. Br J Radiol. 1973;46(547):548–550
- . Treatment and prevention of heparin-induced thrombocytopenia*. Chest. 2008;133(6 suppl):340S–380S
- . Heparin as a cause of thrombus progression. Heparin-associated thrombocytopenia is an important differential diagnosis in paediatric patients even with normal platelet counts. Eur J Pediatr. 1996;155(1):11–14
- . Heparin-induced thrombocytopenia (HIT): An overview of 230 patients treated with orgaran (Org 10172). Thromb Haemost. 1993;70(4):554–561
- . Heparin-induced thrombocytopenia in children. Acta Paediatr. 1993;82(5):495–497
- . Heparin-induced thrombocytopenia in a child. J Pediatr. 1992;121(1):135–138
- . Heparin-induced thrombocytopenia in pediatrics. Semin Thromb Hemost. 2001;27(3):293–299
- . Heparin-induced thrombocytopenia (HIT) in neonates and very young children undergoing congenital cardiac surgery: A likely under-recognized complication with significant morbidity and mortality: Report of 4 sequential cases. J Thromb Haemost. 2003;1(Suppl1):1494a
- . Incidence of heparin-induced thrombocytopenia in a pediatric intensive care population. Blood. 2003;102(Suppl):536a
- Benefit and risk of heparin for maintaining peripheral venous catheters in neonates: A placebo-controlled trial. J Pediatr. 2003;143(6):741–745
- . Heparin-induced thrombocytopenia in children. J Paediatr Child Health. 2003;39(4):289–292
- . Heparin-induced thrombocytopenia-associated thrombosis in pediatric intensive care patients. Pediatrics. 2002;109(1):E10
- . Heparin induced thrombocytopenia in the newborn. J Vasc Surg. 1996;15:306–312
- . What is the potential for overdiagnosis of heparin-induced thrombocytopenia?. Am J Hematol. 2007;82(12):1037–1043
- . Heparin-induced thrombocytopenia in children. In: Warkentin T, Greinacher A editor. Heparin-induced thrombocytopenia. 3rd ed. New York, NY: Marcel Dekker Inc; 2004;p. 553–571
- . Heparin-induced thrombocytopenia in paediatrics: Clinical characteristics, therapy and outcomes. Intensive Care Med. 2004;30(8):1615–1624
- . Pediatric heparin-induced thrombocytopenia: Management with Danaparoid (orgaran). Ann Thorac Surg. 1999;68(3):1076–1078
- . Anticoagulation with recombinant hirudin and danaparoid sodium in pediatric patients. Semin Thromb Hemost. 2002;28(5):447–454
- . Novel paediatric anticoagulants: a review of the current literature. Blood Coagul Fibrinolysis. 2010;21(2):144–151
- . Accidental heparinization of a newborn infant. Am J Dis Child. 1967;114(3):313–319
- . Inadvertent sodium heparin administration to a newborn infant. JAMA. 1965;191:1031–1032
- . Accidental heparinization in the newborn: A case report and brief review of the literature. J Perinatol. 1990;10(4):399–402
- . Accidental heparin poisoning in an infant. Am J Dis Child. 1965;110:210–212
- . Inadvertent heperanization as a complication of intensive care. Clin Res. 1975;23:161A
- . Accidental heparin toxicity in the newborn intensive care unit. J Pediatr. 1978;92(1):115–116
- . FDA drug safety communication: Update: Follow up to the public health alert about changes to the heparin sodium USP monograph. In: Postmarket drug safety information for patients and providers. 2010;15/04/2010 [cited 22/04/2010]; Available from: http://www.fda.gov/Drugs/DrugSafety/PostmarketDrugSafetyInformationforPatientsandProviders/ucm207506.htm
- . Heparin and low-molecular-weight heparin: Mechanisms of action, pharmacokinetics, dosing considerations, monitoring, efficacy, and safety. Chest. 1998;114(5 Suppl):489S–510S
- . Antithrombotic therapy in children. Chest. 1998;114(5 Suppl):748S–769S
- Use of enoxaparin in the treatment of catheter-related arterial thrombosis in infants with congenital heart disease. Cardiol Young. 2006;16(Supplement 2):27
- . The use of enoxaparin in children with acute, nonhemorrhagic ischemic stroke. Pediatr Neurol. 2003;29(4):295–298
- The use of low molecular weight heparin in pediatric patients: A prospective cohort study. J Pediatr. 2000;136(4):439–445
- Determining of trough anti-factor Xa levels in pediatric patients on low molecular weight heparin (LMWH). J Pediatr Hematol Oncol. 1998;20(4):398
- . Use of enoxaparin in a preterm infant. Ann Pharmacother. 2000;34(12):1410–1413
- Prophylactic therapy with enoxaparin during l-asparaginase treatment in children with acute lymphoblastic leukemia. Blood Coagul Fibrinolysis. 2001;12(5):367–370
- Natural history of arterial and venous thrombosis in children treated with low molecular weight heparin: A longitudinal study by ultrasound. J Thromb Haemost. 2004;2(1):42–46
- . Long-term safety and efficacy data on childhood venous thrombosis treated with a low molecular weight heparin: An open-label pilot study of once-daily versus twice-daily enoxaparin administration. Haematologica. 2006;91(12):1701–1704
- . Use of low molecular mass heparin (enoxaparin) in newborn infants: A prospective cohort study of 62 patients. Arch Dis Child Fetal Neonatal Ed. 2003;88(5):F365–F370
- . A dose-finding study of Tinzaparin in pediatric patients. Blood. 2002;100:279a
- . A normogram to establish therapeutic levels of low molecular weight heparin (LMWH), clivarine in children requiring treatment for venous thromboembolism (VTE). Thromb Haemost. 1997;Supplement:1–843
- . The low molecular weight heparin dalteparin for prophylaxis and therapy of thrombosis in childhood: A report on 48 cases. Eur J Pediatr. 1999;158(Suppl 3):S134–S139
- . Decreased concentrations of heparinoids are required to inhibit thrombin generation in plasma from newborns and children compared to plasma from adults due to reduced thrombin potential. Thromb Haemost. 2002;87(4):606–613
- . The in vitro response to low-molecular-weight heparin is not age-dependent in children. Thromb Haemost. 2010;103(4):
- An open-label randomized controlled trial of low molecular weight heparin for the prevention of central venous line-related thrombotic complications in children: The PROTEKT trial. Thromb Res. 2003;109(2–3):101–108
- Enoxaparin for neonatal thrombosis: A call for a higher dose for neonates. Thromb Res. 2008;122(6):826–830
- . Dosing and monitoring of enoxaparin (LMWH) therapy in children. Br J Haematol. 2010;149(5):734–738
- . Low-molecular-weight heparin in pediatric patients with thrombotic disease: A dose finding study. J Pediatr. 1996;128(3):313–318
- . Anticoagulation therapy in children with mechanical prosthetic cardiac valves. Am J Cardiol. 1985;56(8):533–535
- . Anticoagulation with sodium warfarin in children: Effect of a loading regimen. J Pediatr. 1988;113(6):1095–1097
- Venous thrombotic complications (VTE) in children; first analysis of the Canadian registry of VTE. Blood. 1994;83(5):1251–1257
- . Oral anticoagulation in paediatric patients: Dose requirements and complications. Arch Dis Child. 1996;74(3):228–231
- . Low dose oral anticoagulation therapy in Chinese children with congenital heart disease. J Paediatr Child Health. 1998;34(6):563–567
- . Management of oral anticoagulation in a population of children with cardiac disease using a computerised system to support decision-making. Cardiol Young. 2006;16(3):256–260
- Acenocoumarol therapy in pediatric patients. J Thromb Haemost. 2003;1(8):1740–1743
- . Antithrombotic therapy in children and adolescents. Thromb Res. 1986;42(3):289–301
- . Heparin treatment in childhood and its effect on monitoring tests. Aust Paediatr J. 1973;9(5):269–275
- . The use of heparinization to prevent arterial thrombosis after percutaneous cardiac catheterization in children. Circulation. 1974;50(3):565–569
- . Anticoagulation therapy by continuous heparinization in newborn and older infants. J Pediatr. 1982;101(3):
- . Anticoagulant therapy by continuous heparin-antithrombin III infusion in newborns with disseminated intravascular coagulation. Eur J Pediatr. 1985;144(2):191–194
- . Heparinization during percutaneous cardiac catheterization in children. Pediatr Cardiol. 1987;8(3):167–168
- . Rational approach to use of heparin during cardiac catheterization in children. J Am Coll Cardiol. 1995;25(3):725–729
- . Predictors of arterial thrombosis after diagnostic cardiac catheterization in infants and children randomized to two heparin dosages. Catheter Cardiovasc Diagn. 1997;41(4):400–403
- . Individualized heparin and protamine management in infants and children undergoing cardiac operations. Ann Thorac Surg. 2001;71(3):922–927discussion 927–8
- Assessing heparin dosing in neonates on venoarterial extracorporeal membrane oxygenation. ASAIO J. 2007;53(1):111–114
- A comparison of heparin management strategies in infants undergoing cardiopulmonary bypass. Anesth Analg. 2008;106(2):419–425table of contents
- Monitoring unfractionated heparin (UFH) therapy: Which anti-factor Xa assay is appropriate?. Thromb Res. 2007;120(3):347–351
- In vivo age dependency of unfractionated heparin in infants and children. Thromb Res. 2009;123(5):710–714
- Clinical experiences with low-molecular weight heparins in pediatric patients. Thromb Res. 2001;103(5):345–353
- . Aspirin versus low-dose low-molecular-weight heparin: Antithrombotic therapy in pediatric ischemic stroke patients: A prospective follow-up study. Stroke. 2001;32(11):2554–2558
- Dose-finding and pharmacokinetic profiles of prophylactic doses of a low molecular weight heparin (reviparin-sodium) in pediatric patients. Thromb Res. 2003;109(2–3):93–99
- Dose-finding and pharmacokinetics of therapeutic doses of tinzaparin in pediatric patients with thromboembolic events. Thromb Haemost. 2005;94(6):1164–1171
PII: S0268-960X(10)00026-3
doi: 10.1016/j.blre.2010.06.003
© 2010 Elsevier Ltd. All rights reserved.
« Previous
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Blood Reviews
Volume 24, Issue 4
, Pages 151-162
, July 2010
